Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | SCN4A | P35499 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283224 | 0.83 | FFAR4 (0.56) | MAOBMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL20631651 | 0.82 | MAPT (0.54) | MAOBMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL12301124 | 0.80 | MRGPRX4 (0.58) | MAOBMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL12301128 | 0.80 | ENPP2 (0.66) | MAOBMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL15309708 | 0.80 | MAPT (0.51) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| SCHEMBL12330370 | 0.80 | MRGPRX4 (0.55) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| SCHEMBL8621333 | 0.80 | MAPT (0.51) | MAPTMAPK1TDP1L3MBTL1MRGPRX4 | |
| SCHEMBL20741532 | 0.80 | RXRA (0.53) | MAPTMAPK1TDP1L3MBTL1RXRA | |
| SCHEMBL265584 | 0.80 | MAPK1 (0.70) | MAPTMAPK1TDP1L3MBTL1RXRA | |
| SCHEMBL29874217 | 0.80 | MAPK1 (0.70) | MAPTMAPK1TDP1L3MBTL1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009565-A2 | ACYLAMINOTHIAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2004-01-29 | — | — | WO | disclosed |