Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | IL1RN | P18510 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346888 | 1.00 | CTSL (0.54) | CTSLCTSSALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8707008 | 0.89 | ALDH1A1 (0.53) | CTSLCTSSALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6959620 | 0.89 | ALDH1A1 (0.53) | CTSLCTSSALDH1A1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL25265036 | 0.87 | ALDH1A1 (0.51) | CTSLCTSSALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL17402229 | 0.87 | CTSL (0.54) | CTSLCTSSALDH1A1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8712756 | 0.87 | ALDH1A1 (0.51) | CTSLCTSSALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL27573179 | 0.86 | CTSL (0.56) | CTSLCTSSALDH1A1ATMIL1RN | |
| SCHEMBL19545688 | 0.85 | CTSL (0.53) | CTSLCTSSALDH1A1ATMIL1RN | |
| SCHEMBL20804193 | 0.84 | MMP9 (0.52) | CTSLCTSSALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL22346387 | 0.84 | CTSL (0.56) | CTSLCTSSALDH1A1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948693-A | COVALENTLY BONDING SIDE CHAIN OF SELECTED AMINO ACID TO SOLID SUPPORT VIA ACID-LABILE OR PHOTO-LABILE LINKER, PROTECTING C-TERMINUS, SYNTHESIZING POLYPEPTIDE ON N-TERMINUS, DEPROTECTING C-TERMINUS AND CYCLIZING POLYPEPTIDE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1998046247-A1 | SOLID PHASE SYNTHESIS OF IMMUNOSUPPRESSIVE AGENTS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1998-10-22 | — | — | WO | disclosed |