SCHEMBL8347323

SCHEMBL8347323

CCOc1ccc(C(CC[SiH](C)C)c2ccc(F)c(Oc3ccccc3)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.44
CACNA1C Q13936 1/20 0.37
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 3/20 0.34
ATM Q13315 1/20 0.34
PTGS2 P35354 1/20 0.34
DUT P33316 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CNR2 P34972 1/20 0.34
DRD2 P14416 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7929051 0.87 LTA4H (0.53) LTA4HCACNA1CSLC6A2SLC6A4SLC6A3
SCHEMBL6778028 0.83 LTA4H (0.49) LTA4HCACNA1CSLC6A2SLC6A4SLC6A3
SCHEMBL9654106 0.81 MEN1 (0.36) SLC6A2SLC6A4SLC6A3LMNAMAPT
SCHEMBL27851786 0.77 LTA4H (0.44) LTA4HCACNA1CSLC6A2SLC6A4SLC6A3
SCHEMBL5081296 0.77 LTA4H (0.42) LTA4HCACNA1CSLC6A2SLC6A4SLC6A3
SCHEMBL8615546 0.75 LTA4H (0.40) LTA4HCACNA1CSLC6A2SLC6A4SLC6A3
SCHEMBL5001520 0.75 LTA4H (0.44) LTA4HCACNA1CSLC6A2SLC6A4SLC6A3
SCHEMBL10549602 0.75 LTA4H (0.42) LTA4HCACNA1CSLC6A2SLC6A4SLC6A3
SCHEMBL9801523 0.74 LTA4H (0.43) LTA4HCACNA1CSLC6A2SLC6A4SLC6A3
SCHEMBL10837294 0.73 LTA4H (0.42) LTA4HCACNA1CSLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5925663-A Benzimidazole derivatives BAYER AKTIENGESELLSCHAFT (DE) 1999-07-20 US disclosed
US-5888989-A PARAPYRETHROID INSECTICIDE SELECTED FROM THE GROUP CONSISTING OF SILAFLUOFEN AND ETOFENPROX AND ATLEAT ONE ENTOMOPATHOGENIC FUNGUS SELECTED FROM GENERA HIRSUTELLA, VERTICILLIUM, METARHIZIUM, BEAUVERIA, PAECILOMYCES AND NOMURAEA HOECHST AKTIENGESELLSCHAFT (DE) 1999-03-30 US disclosed
US-5792755-A INSECTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1998-08-11 US disclosed
US-5786375-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-07-28 US disclosed
US-5760067-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-06-02 US disclosed
US-5712304-A MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-01-27 US disclosed
US-5703132-A Synergistic combinations of ammonium salts HOECHST SCHERING AGREVO GMBH (DE) 1997-12-30 US disclosed
US-5703010-A Formulations of crop protection agents HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-30 US disclosed
US-5512534-A OIL IN WATER EMULSIONS HAVING INTERFACES CONTAINING LIQUID CRYSTAL AMINO ACID PHOSPHATE SALTS WHICH PREVENT THE HYDROLYSIS OF SENSITIVE MATERIALS IN THE OIL PHASE HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-30 US disclosed
US-5117028-A Catalysis with hexachloroplatinic acid; hydrosilation HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed
EP-0479244-A1 Process for the preparation of 4-ethoxyphenyl-3-arylpropyl-dimethyl silanes Hoechst Schering AgrEvo GmbH (DE) 1992-04-08 EP disclosed