Sugi Predict

Sugi Predict / Compounds / SCHEMBL5081296

SCHEMBL5081296

SCHEMBL5081296

CCOc1ccc(C(CCc2ccc(F)c(Oc3ccccc3)c2)[SiH](C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 1/20 0.42
▸ SLC6A2 P23975 1/20 0.39
▸ SLC6A4 P31645 1/20 0.39
▸ SLC6A3 Q01959 1/20 0.39
▸ MEN1 O00255 2/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ NPSR1 Q6W5P4 2/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ CACNA1C Q13936 1/20 0.35
▸ LMNA P02545 2/20 0.34
▸ CNR2 P34972 1/20 0.34
▸ LPAR1 Q92633 2/20 0.34
▸ LPAR5 Q9H1C0 2/20 0.34
▸ MAPT P10636 2/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9801523 0.85 LTA4H (0.43) LTA4HSLC6A2SLC6A4SLC6A3MEN1
SCHEMBL10549602 0.81 LTA4H (0.42) LTA4HSLC6A2SLC6A4SLC6A3MEN1
SCHEMBL407786 0.80 LTA4H (0.41) LTA4HSLC6A2SLC6A4SLC6A3MEN1
SCHEMBL10549349 0.80 LTA4H (0.41) LTA4HMEN1KMT2ANPSR1L3MBTL1
SCHEMBL10652023 0.78 LTA4H (0.39) LTA4HSLC6A2SLC6A4SLC6A3MEN1
SCHEMBL10650344 0.78 LTA4H (0.39) LTA4HSLC6A2SLC6A4SLC6A3MEN1
SCHEMBL6506489 0.77 SIGMAR1 (0.46) LTA4HCACNA1CLPAR1LPAR5TDP1
SCHEMBL8347323 0.77 LTA4H (0.44) LTA4HSLC6A2SLC6A4SLC6A3MEN1
SCHEMBL7929051 0.77 LTA4H (0.53) LTA4HSLC6A2SLC6A4SLC6A3MEN1
SCHEMBL9331962 0.76 LTA4H (0.43) LTA4HSLC6A2SLC6A4SLC6A3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7445791-B2 Synergistic insecticidal composition containing Chloronicotynyle and Organosphosphorus compounds UNITED PHOSPHORUS, LTD. (IN) 2008-11-04 — — US disclosed
US-7211545-B2 Imidazo[1,2-a]pyrimidine and fungicidal compositions containing thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-01 — — US disclosed
US-20060008493-A1 Synergistic insecticidal composition containing Chloronicotynyle and Organosphosphorus compounds UPL LIMITED (IN) 2006-01-12 — — US disclosed
EP-0989125-B1 Pesticidal furylmethyl cyclopropanecarboxylates SUMITOMO CHEMICAL CO (JP) 2005-03-16 — — EP disclosed
US-20040235865-A1 Imidazo[1,2-a]pyrimidine and fungicidal compositions containing thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-25 — — US disclosed
US-6762321-B2 SUCH AS N-(2-(3,4-DIMETHOXYPHENYL)ETHYL)-3-DIFLUOROMETHOXY-2-(4 -METHYLPHENYL)ACRYLAMIDE; FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-07-13 — — US disclosed
US-20030195354-A1 Amide compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-16 — — US disclosed
EP-1295868-A1 AMIDE COMPOUNDS AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-26 — — EP disclosed
EP-0989125-A1 Pesticidal furylmethyl cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-03-29 — — EP disclosed
US-5925663-A Benzimidazole derivatives BAYER AKTIENGESELLSCHAFT (DE) 1999-07-20 — — US disclosed
US-5792755-A INSECTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1998-08-11 — — US disclosed
US-5786375-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-07-28 — — US disclosed
US-5760067-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-06-02 — — US disclosed
EP-0643037-B1 Ester compound, active agent for controlling noxious insect pests containing the same as active ingredient, intermediate for production of the ester compound, and process for producing the intermediate SUMITOMO CHEMICAL CO (JP) 1998-05-06 — — EP disclosed
US-5712304-A MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-01-27 — — US disclosed
US-5703132-A Synergistic combinations of ammonium salts HOECHST SCHERING AGREVO GMBH (DE) 1997-12-30 — — US disclosed
US-5703010-A Formulations of crop protection agents HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-30 — — US disclosed
US-5550258-A INSECTICIDES, MITICIDES, NEMATOCIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-08-27 — — US disclosed
US-5512534-A OIL IN WATER EMULSIONS HAVING INTERFACES CONTAINING LIQUID CRYSTAL AMINO ACID PHOSPHATE SALTS WHICH PREVENT THE HYDROLYSIS OF SENSITIVE MATERIALS IN THE OIL PHASE HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-30 — — US disclosed
EP-0643037-A1 Ester compound, active agent for controlling noxious insect pests containing the same as active ingredient, intermediate for production of the ester compound, and process for producing the intermediate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040235865-A1 Imidazo[1,2-a]pyrimidine and fungicidal compositions containing thereof CBR1, NAT1, CBR3 LTA4H 3844/4885SLC6A2 4448/4885SLC6A4 4069/4885
US-20030195354-A1 Amide compounds and use thereof CBR1, CBR3, NAT1 LTA4H 1867/4885SLC6A2 4412/4885SLC6A4 3882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.