SCHEMBL8615546

SCHEMBL8615546

CCOc1ccc(C(F)=C(F)C(c2ccc(F)c(Oc3ccccc3)c2)[SiH](C)C)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.40
LMNA P02545 3/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LPAR1 Q92633 5/20 0.35
LPAR5 Q9H1C0 5/20 0.35
CACNA1C Q13936 1/20 0.34
PTGS2 P35354 1/20 0.34
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
DRD2 P14416 1/20 0.33
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
KAT6A Q92794 1/20 0.33
CNR2 P34972 1/20 0.33
POLB P06746 1/20 0.33
CASP6 P55212 1/20 0.33
EGFR P00533 1/20 0.33
LCK P06239 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8615047 0.88 LMNA (0.38) LMNAL3MBTL1LPAR1LPAR5SLC6A4
SCHEMBL8615041 0.88 LMNA (0.38) LMNAL3MBTL1LPAR1LPAR5SLC6A4
SCHEMBL8619898 0.87 PTGER4 (0.37) LMNAL3MBTL1LPAR1LPAR5
SCHEMBL8622010 0.85 LTA4H (0.47) LTA4HLMNAMAPK1L3MBTL1POLB
SCHEMBL8617483 0.80 LTA4H (0.38) LTA4HLMNAMAPK1L3MBTL1
SCHEMBL7929051 0.78 LTA4H (0.53) LTA4HLMNAL3MBTL1CACNA1CPTGS2
SCHEMBL8347323 0.75 LTA4H (0.44) LTA4HLMNAL3MBTL1CACNA1CPTGS2
SCHEMBL6778028 0.74 LTA4H (0.49) LTA4HLMNAL3MBTL1CACNA1CPTGS2
SCHEMBL27487042 0.73 LTA4H (0.50) LTA4HLMNAMAPK1L3MBTL1LPAR1
SCHEMBL5081296 0.73 LTA4H (0.42) LTA4HLMNAMAPK1L3MBTL1LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5710102-A Difluorovinylsilane insecticidal and acaricidal agents AMERICAN CYANAMID COMPANY (US) 1998-01-20 US disclosed