Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.56 |
| ▸ | CDK8 | P49336 | 1/20 | 0.56 |
| ▸ | PROKR1 | Q8TCW9 | 11/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | FASN | P49327 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355763 | 0.87 | MEN1 (0.51) | PROKR1NPC1RAB9AATMHPGD | |
| SCHEMBL8350228 | 0.84 | NPC1 (0.49) | CCNCCDK8PROKR1NPC1RAB9A | |
| SCHEMBL24855522 | 0.83 | ALDH1A1 (0.56) | PROKR1NPC1RAB9AATMHPGD | |
| SCHEMBL29790471 | 0.83 | ALDH1A1 (0.56) | PROKR1NPC1RAB9AATMHPGD | |
| SCHEMBL8347275 | 0.82 | RHOA (0.53) | PROKR1NPC1RAB9AATMMAPT | |
| SCHEMBL8349619 | 0.82 | TACR2 (0.51) | PROKR1HPGDMAPTMGLLLMNA | |
| SCHEMBL8347627 | 0.80 | PDE4B (0.53) | MGLLLMNA | |
| SCHEMBL8352591 | 0.79 | MGLL (0.57) | PROKR1MGLL | |
| SCHEMBL8353784 | 0.77 | SMN1; SMN2 (0.57) | PROKR1GLAMAPTMGLLLMNA | |
| SCHEMBL8350555 | 0.77 | SCD5 (0.53) | MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861416-A | TREATMENT OF ASTHMA OR COUGH | MERRELL PHARMACEUTICALS INC. (US) | 1999-01-19 | — | — | US | disclosed |
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |