Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | HRH1 | P35367 | 7/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926418 | 0.83 | TDP1 (0.51) | TDP1L3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL21433001 | 0.80 | AGBL2 (0.44) | AGBL2CFTRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL3771280 | 0.77 | TDP1 (0.52) | TDP1L3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL27305171 | 0.75 | KMT2A (0.40) | AGBL2CFTRTDP1L3MBTL1ALDH1A1 | |
| Hydrazine SCHEMBL3964002 | 0.75 | TDP1 (0.50) | TDP1L3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL10921134 | 0.75 | NOS3 (0.38) | HRH4HRH3HRH1HRH2 | |
| SCHEMBL8346116 | 0.75 | HRH3 (0.37) | HRH4HRH3HRH1HRH2 | |
| SCHEMBL10377543 | 0.75 | HTT (0.38) | HRH4HRH3HRH1HRH2KMT2A | |
| SCHEMBL10920431 | 0.73 | HRH1 (0.39) | HRH4HRH3HRH1HRH2 | |
| SCHEMBL3925047 | 0.73 | L3MBTL1 (0.47) | AGBL2CFTRL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021870-A1 | ERYTHROMYCIN A 11, 12-CARBAMATE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |