Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6742902 | 0.93 | PYGL (0.49) | ALDH1A1KDM4EKMT2ARAB9ALMNA | |
| SCHEMBL1766160 | 0.85 | LCK (0.60) | ALDH1A1KDM4EKMT2ARAB9ALMNA | |
| SCHEMBL17244918 | 0.84 | SCN9A (0.51) | KDM4ERAB9ANPC1MAPTPOLB | |
| SCHEMBL28252793 | 0.84 | LMNA (0.50) | ALDH1A1KDM4EKMT2ARAB9ALMNA | |
| SCHEMBL17700509 | 0.83 | HTT (0.55) | ALDH1A1KDM4ERAB9ALMNAHTT | |
| SCHEMBL3617721 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2ARAB9AHTT | |
| SCHEMBL2730020 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4EKMT2ARAB9ALMNA | |
| SCHEMBL13596378 | 0.80 | HTT (0.47) | ALDH1A1KDM4ERAB9ALMNAHTT | |
| SCHEMBL28052752 | 0.80 | NPC1 (0.49) | ALDH1A1KDM4EKMT2ARAB9ALMNA | |
| SCHEMBL16200306 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2ARAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5989451-A | Compounds and methods for doping liquid crystal hosts | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1999-11-23 | — | — | US | disclosed |
| WO-1998034995-A1 | COMPOUNDS AND METHODS FOR DOPING LIQUID CRYSTAL HOSTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1998-08-13 | — | — | WO | disclosed |