Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 8/20 | 0.41 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347398 | 0.81 | TGFBR1 (0.40) | TGFBR1TGFBR2PRKD3PRKD1PRKD2 | |
| SCHEMBL8344445 | 0.81 | TGFBR1 (0.44) | TGFBR1TGFBR2PRKD3PRKD1PRKD2 | |
| SCHEMBL8345867 | 0.80 | TGFBR1 (0.51) | TGFBR1TGFBR2PRKD3PRKD1PRKD2 | |
| SCHEMBL8345869 | 0.80 | TGFBR1 (0.46) | TGFBR1TGFBR2PRKD3PRKD1PRKD2 | |
| SCHEMBL8347168 | 0.79 | TGFBR1 (0.47) | TGFBR1TGFBR2PRKD3PRKD1PRKD2 | |
| SCHEMBL8347181 | 0.79 | TGFBR1 (0.47) | TGFBR1TGFBR2PRKD3PRKD1PRKD2 | |
| SCHEMBL8344535 | 0.77 | TGFBR1 (0.41) | TGFBR1TGFBR2PRKD3PRKD1PRKD2 | |
| SCHEMBL8345668 | 0.76 | TGFBR1 (0.40) | TGFBR1TGFBR2PRKD3PRKD1PRKD2 | |
| SCHEMBL8347946 | 0.76 | FLT1 (0.43) | TGFBR1TGFBR2PRKD3PRKD1PRKD2 | |
| SCHEMBL8344223 | 0.76 | TGFBR1 (0.40) | TGFBR1TGFBR2PRKD3PRKD1PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024159-A1 | INHIBITORS OF TFGβ | SCIOS INC. (US) | 2004-03-25 | — | — | WO | disclosed |