Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAS1 | P04201 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348333 | 0.89 | AGTR2 (0.48) | AGTR2AGTR1 | |
| SCHEMBL8550486 | 0.71 | AGTR2 (0.56) | AGTR2 | |
| SCHEMBL7610956 | 0.71 | MAS1 (0.52) | MAS1AGTR2 | |
| SCHEMBL9684086 | 0.70 | SLC6A4 (0.46) | AGTR2AGTR1 | |
| SCHEMBL7611026 | 0.68 | MAS1 (0.52) | MAS1AGTR2AGTR1 | |
| SCHEMBL7612134 | 0.67 | AGTR2 (0.47) | AGTR2AGTR1 | |
| SCHEMBL8353009 | 0.66 | AGTR2 (0.79) | AGTR2AGTR1 | |
| SCHEMBL8348414 | 0.66 | AGTR2 (0.72) | AGTR2AGTR1 | |
| SCHEMBL8348138 | 0.66 | AGTR2 (0.81) | AGTR2AGTR1 | |
| SCHEMBL8345874 | 0.65 | AGTR1 (0.61) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977155-A | CARDIOVASCULAR, KIDNEYS | HOECHST MARION ROUSSEL (FR) | 1999-11-02 | — | — | US | disclosed |