Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652320 | 0.87 | NOS2 (0.41) | HRH1HRH3 | |
| SCHEMBL6530888 | 0.83 | TLR8 (0.41) | TLR8MAPT | |
| SCHEMBL29172695 | 0.81 | KCNH2 (0.43) | TLR8MAPT | |
| SCHEMBL27805707 | 0.81 | TLR8 (0.44) | TLR8 | |
| SCHEMBL10563463 | 0.79 | ATM (0.36) | — | |
| SCHEMBL11064255 | 0.78 | ATM (0.36) | — | |
| SCHEMBL18989817 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL5743709 | 0.76 | ALOX5AP (0.36) | TLR8 | |
| SCHEMBL10392375 | 0.76 | SORD (0.41) | MAPT | |
| SCHEMBL3822501 | 0.76 | NOS2 (0.44) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021870-A1 | ERYTHROMYCIN A 11, 12-CARBAMATE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |