Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10563463 | 0.98 | ATM (0.36) | ATML3MBTL1HIF1AEPAS1TBXAS1 | |
| SCHEMBL10564336 | 0.78 | NCF1 (0.35) | KCNH2SCN5ASCN9ACDC7 | |
| SCHEMBL29172695 | 0.78 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL8348332 | 0.78 | HRH1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL5743709 | 0.76 | ALOX5AP (0.36) | HIF1AEPAS1 | |
| SCHEMBL6530888 | 0.76 | TLR8 (0.41) | L3MBTL1KCNH2 | |
| SCHEMBL4652320 | 0.76 | NOS2 (0.41) | SCN9A | |
| SCHEMBL27805707 | 0.74 | TLR8 (0.44) | PDE3BPDE3A | |
| SCHEMBL10783205 | 0.73 | ALDH1A1 (0.36) | KCNH2SCN5ASCN9ACDC7 | |
| SCHEMBL11814514 | 0.72 | HSP90AA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463005-A | INHIBIT SECRETION OF GASTRIC ACID | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-07-31 | — | — | US | disclosed |
| EP-0060730-A2 | Bicyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | disclosed |