Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.58 |
| ▸ | CTSS | P25774 | 5/20 | 0.49 |
| ▸ | CTSL | P07711 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | GRN | P28799 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CTSV | O60911 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13909109 | 0.92 | CTSK (0.69) | CTSKCTSSCTSLCTSBGRN | |
| SCHEMBL8349746 | 0.86 | CTSK (0.59) | CTSKCTSSCTSLCTSBGRN | |
| SCHEMBL8350078 | 0.82 | CTSK (0.69) | CTSKCTSSCTSLCTSBGRN | |
| SCHEMBL5942080 | 0.78 | CTSK (0.88) | CTSKCTSSCTSLCTSBCCR1 | |
| SCHEMBL5942073 | 0.78 | CTSK (0.88) | CTSKCTSSCTSLCTSBCCR1 | |
| SCHEMBL8349685 | 0.78 | CTSK (0.60) | CTSKCTSSCTSLCTSBGRN | |
| SCHEMBL6237514 | 0.77 | CTSK (0.46) | CTSKCTSSCTSLCTSBUTS2R | |
| SCHEMBL4037045 | 0.76 | CTSK (0.72) | CTSKCTSSCTSLCCR1CTSV | |
| SCHEMBL4046526 | 0.76 | CTSK (0.72) | CTSKCTSSCTSLCCR1CTSV | |
| SCHEMBL8348412 | 0.75 | CTSK (0.71) | CTSKCTSSCTSBCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |