Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.59 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13909109 | 0.92 | CTSK (0.69) | CTSKCTSSCTSLCTSBGRN | |
| SCHEMBL8349685 | 0.92 | CTSK (0.60) | CTSKCTSSCTSLCTSBGRN | |
| SCHEMBL13909099 | 0.89 | PREP (0.48) | CTSKCTSSCTSLCTSBCHRNB2 | |
| SCHEMBL8348404 | 0.86 | CTSK (0.58) | CTSKCTSSCTSLCTSBGRN | |
| SCHEMBL8350078 | 0.84 | CTSK (0.69) | CTSKCTSSCTSLCTSBGRN | |
| SCHEMBL13909120 | 0.84 | CTSK (0.57) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL4043042 | 0.84 | CTSK (0.68) | CTSKCTSSCTSLALDH1A1PREP | |
| SCHEMBL5941468 | 0.83 | CTSK (0.82) | CTSKCTSSALDH1A1PREPFAP | |
| SCHEMBL4041237 | 0.83 | CTSK (0.82) | CTSKCTSSALDH1A1PREPFAP | |
| SCHEMBL4215663 | 0.83 | CTSK (0.82) | CTSKCTSSALDH1A1PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |