Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SDCBP | O00560 | 1/20 | 0.35 |
| ▸ | SDC2 | P34741 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6786407 | 0.91 | L3MBTL1 (0.39) | HSP90AA1KCNH2SMN1; SMN2SSTR4L3MBTL1 | |
| SCHEMBL8348739 | 0.85 | SLC6A4 (0.36) | SSTR4L3MBTL1SDCBPSDC2RAB9A | |
| SCHEMBL8344651 | 0.84 | CYP19A1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL7016547 | 0.78 | HSP90AA1 (0.50) | HSP90AA1KCNH2SMN1; SMN2L3MBTL1SDCBP | |
| SCHEMBL6787040 | 0.77 | SLC6A4 (0.36) | SMN1; SMN2SSTR4L3MBTL1SDCBPSDC2 | |
| SCHEMBL7049482 | 0.75 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL8348150 | 0.73 | L3MBTL1 (0.46) | HSP90AA1KCNH2SMN1; SMN2L3MBTL1SDCBP | |
| SCHEMBL24483689 | 0.72 | ALDH1A1 (0.39) | SMN1; SMN2L3MBTL1ALDH1A1LMNANPC1 | |
| SCHEMBL28409176 | 0.71 | CA14 (0.41) | SSTR4L3MBTL1NFKB1NFKB2RELA | |
| SCHEMBL25359493 | 0.70 | CA14 (0.43) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016583-A1 | SUBSTITUTED GLYCINE DERIVATIVES FOR USE AS MEDICAMENTS | PFIZER LIMITED (GB) | 2004-02-26 | — | — | WO | disclosed |