Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | SDCBP | O00560 | 2/20 | 0.47 |
| ▸ | SDC2 | P34741 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868844 | 0.86 | HSP90AA1 (0.48) | HSP90AA1KCNH2SDCBPSDC2HPGD | |
| SCHEMBL7862203 | 0.84 | PKM (0.44) | SDCBPSDC2HPGDPKMPOLB | |
| SCHEMBL7049482 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2HPGDPOLBKMT2AALDH1A1 | |
| SCHEMBL7874072 | 0.83 | MTNR1A (0.52) | SMN1; SMN2HPGDPKML3MBTL1HTT | |
| SCHEMBL7012446 | 0.82 | HSP90AA1 (0.54) | HSP90AA1KCNH2SDCBPSDC2SMN1; SMN2 | |
| SCHEMBL8348150 | 0.81 | L3MBTL1 (0.46) | HSP90AA1KCNH2SDCBPSDC2SMN1; SMN2 | |
| SCHEMBL7651344 | 0.79 | HSP90AA1 (0.51) | HSP90AA1KCNH2SDCBPSDC2SMN1; SMN2 | |
| SCHEMBL7046265 | 0.79 | SDCBP (0.54) | HSP90AA1KCNH2SDCBPSDC2SMN1; SMN2 | |
| SCHEMBL8348656 | 0.78 | HSP90AA1 (0.36) | HSP90AA1KCNH2SDCBPSDC2SMN1; SMN2 | |
| SCHEMBL18295921 | 0.78 | L3MBTL1 (0.55) | SDCBPSDC2SMN1; SMN2L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | SULT1E1, RRS1, SHH | HSP90AA1 4038/4885KCNH2 164/4885SDCBP 3953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.