Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | RAF1 | P04049 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 2/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CSF1R | P07333 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295339 | 0.92 | TP53 (0.63) | MCHR1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL21295536 | 0.91 | KDR (0.61) | MCHR1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL8350552 | 0.90 | KMT2A (0.72) | KMT2AMEN1MAPTRAB9AALDH1A1 | |
| SCHEMBL6110029 | 0.88 | MCHR1 (0.65) | MCHR1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL19427494 | 0.86 | RAB9A (0.73) | KMT2AMEN1MAPTRAB9AALDH1A1 | |
| SCHEMBL21295375 | 0.85 | TP53 (0.66) | KMT2AMEN1MAPTRAB9AALDH1A1 | |
| SCHEMBL30743987 | 0.85 | TP53 (0.66) | KMT2AMEN1MAPTRAB9AALDH1A1 | |
| SCHEMBL21295574 | 0.85 | NPC1 (0.76) | KMT2AMEN1MAPTRAB9AALDH1A1 | |
| SCHEMBL8345734 | 0.84 | KMT2A (0.78) | KMT2AMEN1MAPTRAB9AALDH1A1 | |
| SCHEMBL21295338 | 0.84 | TP53 (0.83) | KMT2AMEN1MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069823-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2004-08-19 | — | — | WO | disclosed |
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |