Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | AHR | P35869 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 9/20 | 0.62 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | CASP1 | P29466 | 3/20 | 0.62 |
| ▸ | CASP7 | P55210 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963526 | 0.91 | MEN1 (0.61) | KMT2AMEN1NR1I2AHRMAPT | |
| SCHEMBL12933429 | 0.87 | KMT2A (0.58) | KMT2AMEN1NR1I2AHRMAPT | |
| SCHEMBL8348445 | 0.86 | KMT2A (0.67) | KMT2AMEN1NR1I2AHRMAPT | |
| SCHEMBL8832163 | 0.78 | MEN1 (1.00) | KMT2AMEN1NR1I2AHRMAPT | |
| SCHEMBL8349393 | 0.77 | MEN1 (0.70) | KMT2AMEN1NR1I2AHRMAPT | |
| SCHEMBL11180483 | 0.76 | MEN1 (0.68) | KMT2AMEN1NR1I2AHRMAPT | |
| SCHEMBL16621922 | 0.75 | MEN1 (0.68) | KMT2AMEN1NR1I2AHRMAPT | |
| SCHEMBL1078343 | 0.73 | HDAC1 (0.57) | — | |
| SCHEMBL8832460 | 0.73 | MEN1 (0.65) | KMT2AMEN1NR1I2AHRMAPT | |
| SCHEMBL8832269 | 0.70 | KMT2A (0.53) | KMT2AMEN1NR1I2AHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069823-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2004-08-19 | — | — | WO | disclosed |