Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | KLK7 | P49862 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349072 | 0.99 | TSHR (0.66) | TSHRKLK7NPC1RAB9AMAPK1 | |
| SCHEMBL8346775 | 0.76 | TSHR (0.58) | TSHRKLK7 | |
| SCHEMBL8348907 | 0.72 | TSHR (0.51) | TSHRNPC1RAB9ALMNA | |
| SCHEMBL6762194 | 0.70 | TSHR (0.55) | TSHRNPC1RAB9AEPHX1 | |
| SCHEMBL16936035 | 0.70 | KLK7 (1.00) | TSHRKLK7NPC1RAB9A | |
| SCHEMBL18648119 | 0.69 | TSHR (0.67) | TSHRNPC1RAB9AEPHX1 | |
| SCHEMBL30846710 | 0.67 | KMT2A (0.57) | TSHRKLK7NPC1RAB9AMAPK1 | |
| SCHEMBL18354572 | 0.67 | KLK7 (1.00) | KLK7 | |
| SCHEMBL18189140 | 0.65 | TSHR (0.50) | TSHR | |
| SCHEMBL7385405 | 0.65 | DRD2 (0.41) | TSHRNPC1RAB9AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003101941-A2 | ALPHA ACYLOXYACETAMIDES FOR KALLIKREIN AND UROKINASE INHIBITION | GENZYME CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |