Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238332 | 0.84 | KMT2A (0.44) | KMT2ATSHRHPGD | |
| SCHEMBL830996 | 0.83 | KMT2A (0.50) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL28236554 | 0.82 | EPHX2 (0.47) | KMT2AHPGDFAAH | |
| SCHEMBL29135345 | 0.82 | EPHX2 (0.47) | KMT2AHPGDFAAH | |
| SCHEMBL28237683 | 0.78 | LMNA (0.53) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL27740658 | 0.76 | HSD11B1 (0.47) | ELANESMN1; SMN2HSD11B1 | |
| SCHEMBL9776664 | 0.74 | KMT2A (0.57) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL29245395 | 0.74 | KMT2A (0.57) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL28799780 | 0.72 | CA1 (0.51) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL9815773 | 0.72 | ALDH1A1 (0.50) | KMT2ATSHRGAAELANEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999033468-A9 | METHOD FOR TREATING HYPEROXIA | CELL THERAPEUTICS INC (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999033468-A1 | METHOD FOR TREATING HYPEROXIA | CELL THERAPEUTICS, INC. (US) | 1999-07-08 | — | — | WO | disclosed |