Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.49 |
| ▸ | GABRE | P78334 | 1/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21154486 | 0.83 | TRPV1 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21154241 | 0.83 | TRPV1 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21154197 | 0.81 | FAAH (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21154508 | 0.77 | PTGES (0.49) | PTGESPTGS2HCRTR2HCRTR1 | |
| SCHEMBL21154185 | 0.77 | PTGES (0.49) | PTGESPTGS2HCRTR2HCRTR1 | |
| SCHEMBL29293532 | 0.77 | PTGES (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL24331257 | 0.77 | PTGES (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4697951 | 0.76 | HTR3A (0.67) | — | |
| SCHEMBL19698128 | 0.76 | PTGES (0.56) | PTGESPTGS2HCRTR2HCRTR1 | |
| SCHEMBL29293567 | 0.76 | KDM4E (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |