Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357015 | 0.90 | ESR1 (0.69) | ESR1ESR2SHBGKEAP1MAPT | |
| SCHEMBL3710965 | 0.86 | SHBG (0.61) | ESR1ESR2SHBGKEAP1MAPT | |
| SCHEMBL30375336 | 0.86 | SHBG (0.61) | ESR1ESR2SHBGKEAP1MAPT | |
| SCHEMBL4063026 | 0.86 | SHBG (0.61) | ESR1ESR2SHBGKEAP1MAPT | |
| SCHEMBL10005890 | 0.86 | ESR1 (0.61) | ESR1ESR2KEAP1MAPTCA1 | |
| SCHEMBL8349574 | 0.86 | ESR1 (0.61) | ESR1ESR2KEAP1MAPTCA1 | |
| SCHEMBL16592194 | 0.86 | ESR1 (0.61) | ESR1ESR2KEAP1MAPTCA1 | |
| SCHEMBL5527320 | 0.86 | ESR1 (0.61) | ESR1ESR2SHBGKEAP1CA1 | |
| SCHEMBL25518105 | 0.85 | KEAP1 (0.52) | ESR1ESR2KEAP1MAPTCA1 | |
| SCHEMBL8351876 | 0.83 | ESR1 (0.69) | ESR1ESR2SHBGMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853949-A | Method of synthesizing polyphenol compound and positive working photoresist composition comprising polyphenol compound | FUJI PHOTO FILM CO., LTD. (JP) | 1998-12-29 | — | — | US | disclosed |