Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349531 | 0.91 | TDP1 (0.68) | TDP1LMNASCN5ACYP1A2MAOA | |
| SCHEMBL30285481 | 0.87 | TDP1 (0.58) | TDP1LMNASCN5ACYP1A2MAOA | |
| SCHEMBL12088129 | 0.81 | TDP1 (0.61) | TDP1LMNASCN5ACYP1A2MAOA | |
| SCHEMBL29016000 | 0.77 | RAB9A (0.50) | TDP1LMNASCN5ACYP1A2MAOA | |
| SCHEMBL223441 | 0.77 | TDP1 (1.00) | TDP1LMNAMAPK1SLC6A3CYP3A4 | |
| SCHEMBL416566 | 0.77 | TDP1 (0.91) | TDP1LMNACYP1A2MAPK1SLC6A3 | |
| SCHEMBL9377743 | 0.76 | TDP1 (0.70) | TDP1LMNASCN5ACYP1A2MAPK1 | |
| SCHEMBL29143435 | 0.76 | LMNA (0.77) | LMNASCN5ACYP1A2MAOACNR1 | |
| Hydrochloric Acid SCHEMBL1067125 | 0.75 | TDP1 (0.68) | TDP1LMNASCN5ACYP1A2MAPK1 | |
| SCHEMBL17061429 | 0.75 | ESR1 (0.64) | TDP1LMNAMAPK1SLC6A3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999032649-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL 1,3-AMINOALCOHOLS | BIOCATALYTICS, INC. (US) | 1999-07-01 | — | — | WO | disclosed |