Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343720 | 0.85 | MEN1 (0.54) | HPSEKMT2AMEN1RAB9ATP53 | |
| SCHEMBL28409827 | 0.85 | KCNK3 (0.78) | HPSEKCNK9KCNK3KMT2AMEN1 | |
| SCHEMBL8461683 | 0.81 | MEN1 (0.73) | HPSEKCNK9KCNK3KMT2AMEN1 | |
| SCHEMBL9249052 | 0.80 | HPSE (0.84) | HPSEKCNK9KCNK3KMT2AMEN1 | |
| Dimethylamine SCHEMBL9292692 | 0.78 | MEN1 (0.69) | HPSEKCNK9KCNK3KMT2AMEN1 | |
| SCHEMBL8462114 | 0.78 | KMT2A (0.69) | HPSEKCNK9KCNK3KMT2AMEN1 | |
| SCHEMBL19501278 | 0.78 | SIRT1 (0.84) | HPSEKCNK9KCNK3KMT2AMEN1 | |
| SCHEMBL8346108 | 0.78 | KMT2A (0.60) | HPSEKMT2AMEN1RAB9AFFAR1 | |
| SCHEMBL8457167 | 0.78 | ADORA3 (0.71) | HPSEKCNK9KCNK3KMT2AMEN1 | |
| SCHEMBL3659389 | 0.77 | FFAR1 (0.79) | HPSEKCNK9KCNK3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36477-E | 4-(3,5-BIS(TRIMETHYLSILYLPHENYL)CARBOXAMIDO)BENZOIC ACID; DIFFERENTIATION-INDUCING REAGENT OR CELLS; ANTICARCINOGENTIC, -TUMOR,-INFLAMMATORY AND -PROLIFERATIVE AGENTS; PSORIASIS; LEUKEMIA; IMMUNOLOGY | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0337176-B1 | Novel benzoic acid derivatives and process for preparing the same | SHUDO KOICHI (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5155249-A | Differentiating neoplastic cells, treating psoriasis, immune or inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| US-5081271-A | Differentiation-inducing agent for neoplastic cells; therapeutic agent for psoriasis or immune and inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0337176-A2 | Novel benzoic acid derivatives and process for preparing the same | Shudo, Koichi, Prof. Dr. (JP) | 1989-10-18 | — | — | EP | disclosed |