Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.83 |
| ▸ | MEN1 | O00255 | 3/20 | 0.83 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.77 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.75 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.75 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | PARP1 | P09874 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679144 | 0.96 | KMT2A (0.90) | HPSEKMT2AMEN1NR1H4KCNK3 | |
| Hydrochloric Acid SCHEMBL2106175 | 0.94 | KMT2A (0.87) | HPSEKMT2AMEN1NR1H4KCNK3 | |
| SCHEMBL30686768 | 0.92 | MEN1 (0.83) | HPSEKMT2AMEN1NR1H4KCNK3 | |
| SCHEMBL13381198 | 0.92 | L3MBTL1 (0.82) | HPSEKMT2AMEN1NR1H4KCNK3 | |
| SCHEMBL23070423 | 0.92 | KMT2A (0.80) | HPSEKMT2AMEN1NR1H4KCNK3 | |
| SCHEMBL14075235 | 0.92 | PARP1 (0.78) | HPSEKMT2AMEN1NR1H4KCNK3 | |
| SCHEMBL2076281 | 0.92 | HPSE (0.72) | HPSEKMT2AMEN1NR1H4KCNK3 | |
| SCHEMBL6865518 | 0.92 | HPSE (0.72) | HPSEKMT2AMEN1NR1H4KCNK3 | |
| SCHEMBL1814173 | 0.92 | KCNK3 (0.82) | HPSEKMT2AMEN1NR1H4KCNK3 | |
| SCHEMBL1817262 | 0.92 | HPSE (0.72) | HPSEKMT2AMEN1NR1H4KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995017321-A1 | AIRBAG CONTAINING LIQUID CRYSTALLINE POLYMER BLEND | AKZO NOBEL N.V. (NL) | 1995-06-29 | — | — | WO | claimed |
| WO-1994011417-A1 | THERMOTROPIC LIQUID CRYSTALLINE POLYAMIDE | AKZO NOBEL INC. (US) | 1994-05-26 | — | — | WO | claimed |
| US-5286838-A | Copolymer of thermoplastic aliphatic polyamide and mesogen with ortho-and/or meta-linked aromatic groups | AKZO N.V. (NL) | 1994-02-15 | — | — | US | claimed |
| US-20100204219-A1 | AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE | THE GENETICS COMPANY, INC. (CH) | 2010-08-12 | — | — | US | disclosed |
| US-20100204219-A1 | AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE | THE GENETICS COMPANY, INC. (CH) | 2010-08-12 | — | — | US | disclosed |
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-04-01 | — | — | US | disclosed |
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-04-01 | — | — | US | disclosed |
| WO-1995017321-A1 | AIRBAG CONTAINING LIQUID CRYSTALLINE POLYMER BLEND | AKZO NOBEL N.V. (NL) | 1995-06-29 | — | — | WO | disclosed |
| US-5286838-A | Copolymer of thermoplastic aliphatic polyamide and mesogen with ortho-and/or meta-linked aromatic groups | AKZO N.V. (NL) | 1994-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204219-A1 | AROMATIC 1,4-DI-CARBOXYLAMIDES AND THEIR USE | CBR3, CYCS, CYC1 | HPSE 4589/4885KMT2A 2067/4885MEN1 2291/4885 |
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | HMOX1, HMOX2, PPOX | HPSE 560/4885KMT2A 3310/4885MEN1 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.