Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8511036 | 0.78 | CACNA2D1 (0.31) | CACNA2D1CACNA1BCACNB1CACNA1CLMNA | |
| SCHEMBL8350643 | 0.77 | MAPT (0.50) | MAPTMEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL8350645 | 0.66 | MAPT (0.52) | MAPTTSHRALDH1A1KDM4ELMNA | |
| SCHEMBL8350338 | 0.65 | MAPT (0.55) | MAPTTSHRKMT2AALDH1A1KDM4E | |
| SCHEMBL14860144 | 0.65 | CACNA2D1 (0.66) | SLC6A4HTR2ACACNA2D1CACNA1BCACNB1 | |
| SCHEMBL8356732 | 0.64 | SMN1; SMN2 (0.43) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28360934 | 0.64 | ALDH1A1 (0.55) | SLC6A4HTR2AHTR2CMAPTMEN1 | |
| SCHEMBL3436279 | 0.62 | MAPT (0.57) | SLC6A4MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL11173493 | 0.61 | ATM (0.45) | MEN1KMT2ACACNA2D1CACNA1BCACNB1 | |
| SCHEMBL4714358 | 0.61 | KCNQ2 (0.43) | SLC6A4MAPTMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031096-A1 | PIPERAZINE DERIVATIVES USEFUL AS HYPOGLYCEMIC AGENTS | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | claimed |