Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965420 | 0.84 | PTGDR2 (0.61) | PTGDR2PTGDR | |
| SCHEMBL29986862 | 0.73 | TAAR1 (0.71) | SIGMAR1CHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL21002016 | 0.73 | TAAR1 (0.71) | SIGMAR1CHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL8355205 | 0.71 | PPARG (0.46) | PTGDR2 | |
| SCHEMBL12630196 | 0.70 | SIGMAR1 (0.66) | SIGMAR1CHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL21002162 | 0.70 | TAAR1 (0.71) | SIGMAR1CHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL21002124 | 0.69 | TAAR1 (0.69) | SIGMAR1CHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL4060273 | 0.69 | TAAR1 (0.69) | SIGMAR1CHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL11536038 | 0.67 | ABCB1 (0.59) | SIGMAR1CHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL5077290 | 0.67 | MTNR1A (0.53) | SIGMAR1CHRM2CHRM1CHRM3PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935985-A | Phenoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5703099-A | TREATMENT OF THROMBOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASES, GASTRIC ULCER OR HYPERTENSION | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |