SCHEMBL8350923

SCHEMBL8350923

C=C(C(=O)O)C(C=C(CCCC)C(=O)O)CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 3/20 0.35
GRIK1 P39086 1/20 0.34
PPARG P37231 5/20 0.33
ALOX5 P09917 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
PTGES O14684 1/20 0.33
CA2 P00918 1/20 0.32
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 3/20 0.31
AKR1B1 P15121 1/20 0.31
TP53 P04637 1/20 0.31
PPARD Q03181 4/20 0.31
PPARA Q07869 4/20 0.31
TSHR P16473 3/20 0.31
GPR84 Q9NQS5 3/20 0.31
HDAC11 Q96DB2 3/20 0.31
TDP1 Q9NUW8 2/20 0.31
SLC22A6 Q4U2R8 1/20 0.31
SLC22A8 Q8TCC7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8355107 0.94 GPR84 (0.40) PPARGALDH1A1PPARDPPARATSHR
SCHEMBL7017093 0.90 FFAR3 (0.32) GRIK1
SCHEMBL6696578 0.89 CAMK2A (0.32)
SCHEMBL7879109 0.83 FFAR4 (0.39) APEX1PPARGALDH1A1PPARDPPARA
SCHEMBL4442361 0.83 FFAR1 (0.42) PPARGALDH1A1PPARDPPARATSHR
SCHEMBL8769847 0.82 ACHE (0.35) GRIK1CA2MAPK1AKR1B1TSHR
SCHEMBL158481 0.81 APEX1 (0.36) APEX1GRIK1PPARGALOX5CES2
SCHEMBL18797243 0.81 APEX1 (0.31) APEX1
SCHEMBL9817727 0.80 TSHR (0.38) APEX1PPARGCA2MAPK1ALDH1A1
SCHEMBL7262843 0.79 DNM1 (0.37) APEX1PPARGALDH1A1AKR1B1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5882841-A ULTRAHIGH CONTRAST, STORAGE STABILITY, UNIFORMITY, POLYMER PARTICLES CONTAINING A HYDRAZINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-03-16 US disclosed
EP-0317983-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1994-06-01 EP disclosed
US-5200304-A Having uniform cyan dye density; capable of being processed at high speeds, storage stable FUJI PHOTO FILM CO., LTD. (JP) 1993-04-06 US disclosed
US-5100771-A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL WITH WATER INSOLUBLE ORGANIC SOLVENT SOLUBLE POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1992-03-31 US disclosed
US-5047314-A Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-09-10 US disclosed
EP-0435179-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-07-03 EP disclosed
EP-0317983-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-31 EP disclosed