Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963490 | 0.88 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1HSD17B10GAA | |
| SCHEMBL14424854 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1HSD17B10GAA | |
| SCHEMBL13713684 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1HSD17B10GAA | |
| SCHEMBL10272924 | 0.81 | MAPT (0.58) | ALDH1A1KMT2AMEN1GAAHTT | |
| SCHEMBL14425114 | 0.81 | LMNA (0.46) | ALDH1A1KMT2AMEN1HSD17B10GAA | |
| SCHEMBL10273104 | 0.78 | ALDH1A1 (0.31) | ALDH1A1KMT2AMEN1HSD17B10GAA | |
| SCHEMBL4088527 | 0.78 | GAA (0.43) | ALDH1A1KMT2AMEN1HSD17B10GAA | |
| SCHEMBL2759555 | 0.72 | MAP2K1 (0.46) | ALDH1A1KMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL4093729 | 0.71 | CHEK1 (0.44) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL25370588 | 0.70 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |