Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351467 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AHSD17B10GAA | |
| SCHEMBL12963490 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AHSD17B10GAA | |
| SCHEMBL12933352 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AHSD17B10GAA | |
| SCHEMBL4088527 | 0.74 | GAA (0.43) | ALDH1A1MEN1KMT2AHSD17B10GAA | |
| SCHEMBL14424854 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AHSD17B10GAA | |
| SCHEMBL14425114 | 0.69 | LMNA (0.46) | ALDH1A1MEN1KMT2AHSD17B10GAA | |
| SCHEMBL4093729 | 0.68 | CHEK1 (0.44) | ALDH1A1MEN1KMT2AGAAPIK3CD | |
| SCHEMBL6244966 | 0.68 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL10272924 | 0.67 | MAPT (0.58) | ALDH1A1MEN1KMT2AGAAHTT | |
| SCHEMBL2733616 | 0.66 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595343-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2009-09-29 | — | — | US | disclosed |