Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | PARG | Q86W56 | 3/20 | 0.49 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843229 | 0.80 | ALDH1A1 (0.56) | PIK3CGHTTLMNABRPF1ALDH1A1 | |
| SCHEMBL5987056 | 0.79 | PIK3CG (0.58) | PIK3CGPKMHTTLMNAMITF | |
| Ammonia Solution, Strong SCHEMBL1842927 | 0.79 | ALDH1A1 (0.55) | PIK3CGHTTLMNABRPF1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16736534 | 0.79 | ALDH1A1 (0.55) | PIK3CGHTTLMNABRPF1ALDH1A1 | |
| SCHEMBL12080952 | 0.78 | PIK3CG (0.57) | PIK3CGPKMHTTLMNAMITF | |
| SCHEMBL6352512 | 0.78 | PIK3CG (0.57) | PIK3CGPKMHTTLMNAMITF | |
| SCHEMBL22904133 | 0.78 | PIK3CG (0.57) | PIK3CGPKMHTTLMNAMITF | |
| SCHEMBL12799219 | 0.78 | PIK3CG (0.57) | PIK3CGPKMHTTLMNAMITF | |
| SCHEMBL29433546 | 0.78 | KDM4E (0.50) | HTTBRPF1ALDH1A1KDM4EMAPT | |
| SCHEMBL351390 | 0.78 | KDM4E (0.50) | HTTBRPF1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |
| EP-0761764-B1 | Water-insoluble azo colouring agents derived from aminoquinazolinediones | CLARIANT GMBH (DE) | 1999-12-29 | — | — | EP | disclosed |
| US-5747566-A | MONOAZO DYES FORMED BY DIAZOTIZATION AN AMINE COMPOUND | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-05 | — | — | US | disclosed |
| EP-0761764-A1 | Water-insoluble azo colouring agents derived from aminoquinazolinediones | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-12 | — | — | EP | disclosed |