SCHEMBL351390

SCHEMBL351390

Cn1c2ccc(N)cc2c2cc(N)ccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.50
MAPT P10636 5/20 0.50
ALDH1A1 P00352 5/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
HPGD P15428 3/20 0.50
HSD17B10 Q99714 3/20 0.50
HTT P42858 2/20 0.50
MAPK1 P28482 1/20 0.50
HBB P68871 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
BRPF1 P55201 2/20 0.48
PRKCI P41743 1/20 0.48
GPR3 P46089 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
PABPC1 P11940 1/20 0.42
HCRTR1 O43613 1/20 0.41
TLR9 Q9NR96 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29433546 1.00 KDM4E (0.50) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL20384886 0.89 ACHE (0.47) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL29565790 0.89 MEN1 (0.66) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL728256 0.89 MEN1 (0.66) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL10871998 0.88 MAPT (0.45) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL3874806 0.88 BCHE (0.56) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL18268245 0.88 MEN1 (0.42) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL18268243 0.83 MEN1 (0.48) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL3874932 0.82 KDM4E (0.45) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL27673129 0.82 LIMK1 (0.45) KDM4EMAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 542 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117940842-A Liquid crystal aligning agent, liquid crystal alignment film, method for manufacturing liquid crystal display element, and liquid crystal display element 日产化学株式会社 2024-04-26 CN claimed
CN-117916657-A Liquid crystal aligning agent, liquid crystal alignment film, method for manufacturing liquid crystal display element, and liquid crystal display element 日产化学株式会社 2024-04-19 CN claimed
CN-116868114-A Liquid crystal aligning agent, liquid crystal alignment film, method for manufacturing liquid crystal display element, and liquid crystal display element 日产化学株式会社 2023-10-10 CN claimed
CN-116234856-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2023-06-06 CN claimed
CN-115380244-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2022-11-22 CN claimed
CN-113150445-B Water-blocking oxygen-blocking polyolefin material and preparation method and application thereof 江苏南方包装有限公司 2022-06-24 CN claimed
CN-113150445-A Water-blocking oxygen-blocking polyolefin material and preparation method and application thereof 江苏南方包装有限公司 2021-07-23 CN claimed
US-20190128890-A1 METHODS RELATED TO VOLATILE COMPOUNDS IN GENITOURINARY CANCERS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2019-05-02 US claimed
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INST SCI & TECH (KR) 2018-03-08 US claimed
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-07-07 US claimed
EP-2940015-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT Korea Advanced Institute of Science and Technology (KR) 2015-11-04 EP claimed
CN-101812304-B Liquid crystal aligning agent, liquid crystal display device and fabricating method thereof JSR CO LTD 2014-03-19 CN claimed
US-20080098535-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof GLENN ROBERT W JR 2008-05-01 US claimed
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-10-06 US claimed
US-20250257265-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT NISSAN CHEMICAL CORPORATION (JP) 2025-08-14 US disclosed
WO-2025127092-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2025-06-19 WO disclosed
WO-2025121249-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2025-06-12 WO disclosed
EP-1735059-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2006-12-27 EP disclosed
WO-2005099656-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-10-27 WO disclosed
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof KRT18, CKMT1A; CKMT1B, TUBB6 KDM4E 1549/4885MAPT 420/4885ALDH1A1 660/4885
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT RICTOR, SGTA, SLC43A1 KDM4E 1523/4885MAPT 524/4885ALDH1A1 1659/4885
US-20080098535-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof KRT18, CKMT1A; CKMT1B, TUBB6 KDM4E 1549/4885MAPT 420/4885ALDH1A1 660/4885
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT SGTA, RICTOR, SLC43A1 KDM4E 1130/4885MAPT 394/4885ALDH1A1 1627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.