SCHEMBL1843229

SCHEMBL1843229

Cn1c(=O)n(C)c2cc(N)ccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
SMN1; SMN2 Q16637 6/20 0.56
BRPF1 P55201 4/20 0.56
KDM4E B2RXH2 4/20 0.56
HSD17B10 Q99714 3/20 0.56
BRD4 O60885 2/20 0.56
ATAD2 Q6PL18 1/20 0.53
GAA P10253 3/20 0.52
MAPT P10636 1/20 0.52
GFER P55789 1/20 0.52
TP53 P04637 1/20 0.49
S100B P04271 1/20 0.48
GLA P06280 1/20 0.47
PIK3CD O00329 1/20 0.47
PIK3CA P42336 1/20 0.47
PIK3CB P42338 1/20 0.47
PIK3CG P48736 1/20 0.47
PRKCI P41743 1/20 0.44
HTT P42858 2/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL1842927 0.98 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2BRPF1KDM4EHSD17B10
Hydrochloric Acid SCHEMBL16736534 0.98 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2BRPF1KDM4EHSD17B10
SCHEMBL25406024 0.81 ALDH1A1 (0.75) ALDH1A1SMN1; SMN2BRPF1KDM4EHSD17B10
SCHEMBL30349665 0.81 HPD (0.49) ALDH1A1SMN1; SMN2BRPF1KDM4EHSD17B10
SCHEMBL28968224 0.81 ALDH1A1 (0.75) ALDH1A1SMN1; SMN2BRPF1KDM4EHSD17B10
SCHEMBL8351561 0.80 PIK3CG (0.61) ALDH1A1SMN1; SMN2BRPF1KDM4EHSD17B10
SCHEMBL10145973 0.80 MAPK14 (0.48) ALDH1A1SMN1; SMN2BRPF1KDM4EHSD17B10
SCHEMBL25408758 0.80 BRPF1 (0.47) ALDH1A1SMN1; SMN2BRPF1KDM4EHSD17B10
SCHEMBL25406066 0.79 DRD2 (0.51) ALDH1A1BRPF1KDM4EATAD2GAA
SCHEMBL28968245 0.79 PIK3CA (0.52) ALDH1A1BRPF1KDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719391-A2 TRIPLE KINASE INHIBITORS Unogen Biotech Ltd. (US) 2026-04-08 EP disclosed
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-31 US disclosed
US-12590066-B2 Fused-heterocyclyl-carbonohydrazonoyl dicyanide compounds and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-31 US disclosed
US-20260085050-A1 TRIPLE KINASE INHIBITORS UNOGEN BIOTECH LTD (US) 2026-03-26 US disclosed
WO-2025096771-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 WO disclosed
CN-113727972-B Novel hydrazone derivatives having terminal amine groups substituted with aryl or heteroaryl groups and use thereof 韩国科学技术研究院 2024-12-27 CN disclosed
US-20240417388-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-12-19 US disclosed
WO-2024249831-A2 TRIPLE KINASE INHIBITORS UNOGEN BIOTECH LTD. (US) 2024-12-05 WO disclosed
US-12110286-B2 Benzimidazolone derived inhibitors of BCL6 CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2024-10-08 US disclosed
US-20240327393-A1 FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd. (KY) 2024-10-03 US disclosed
US-20070037791-A1 serine/threonine kinase inhibitors, useful for therapy and/or prophylaxis of cancers in mammals HOFFMAN-LAROUCHE, INC. 2007-02-15 US disclosed
US-20070037791-A1 serine/threonine kinase inhibitors, useful for therapy and/or prophylaxis of cancers in mammals HOFFMAN-LAROUCHE, INC. 2007-02-15 US disclosed
EP-1120421-B1 New triphendioxazine compounds CLARIANT FINANCE BVI LTD (VG) 2005-02-09 EP disclosed
US-6617453-B1 Preparing these triphendioxazine compounds by a cyclization step conducted in the presence of manganese dioxide and concentrated sulphuric acid. CLARIANT FINANCE (BVI) LIMITED (VG) 2003-09-09 US disclosed
EP-0911337-B1 Process for the preparation of triphendioxazine compounds CLARIANT FINANCE BVI LTD (VG) 2003-02-26 EP disclosed
US-6355795-B1 PIGMENTS POSSESSING HIGH FASTNESS TO SOLVENTS, MIGRATION AND LIGHT, WHICH HAVE GOOD THERMAL STABILITIES AND HIGH TINTING POWER AND ARE ALSO EASILY DISPERSIBLE CLARIANT FINANCE (BVI) LIMITED (BV) 2002-03-12 US disclosed
EP-1120421-A2 New triphendioxazine compounds Clariant Finance (BVI) Limited (VG) 2001-08-01 EP disclosed
EP-1120420-A2 New triphendioxazine compounds Clariant Finance (BVI) Limited (VG) 2001-08-01 EP disclosed
US-6255482-B1 PREPARING CHLORINE-CONTAINING TRIPHENDIOXAZINE COMPOUNDS USEFUL AS PIGMENTS POSSESSING HIGH FASTNESS TO SOLVENTS, MIGRATION, AND LIGHT, WHICH HAVE GOOD THERMAL STABILITIES AND HIGH TINTING POWER CLARIANT FINANCE (BVI) LIMITED (VG) 2001-07-03 US disclosed
EP-0911337-A1 New triphendioxazine compounds Clariant Finance (BVI) Limited (VG) 1999-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085050-A1 TRIPLE KINASE INHIBITORS ALK, ERBB2, ERBB3 ALDH1A1 2170/4885SMN1; SMN2 3559/4885BRPF1 4188/4885
US-20240327393-A1 FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF AIFM2, GPX1, GPX4 ALDH1A1 1306/4885SMN1; SMN2 1657/4885BRPF1 2227/4885
US-20240417388-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 BCL6, BCL6B, BCL3 ALDH1A1 1654/4885SMN1; SMN2 3864/4885BRPF1 116/4885
US-20070037791-A1 serine/threonine kinase inhibitors, useful for therapy and/or prophylaxis of cancers in mammals RAF1, CHEK1, BRAF ALDH1A1 2759/4885SMN1; SMN2 3254/4885BRPF1 2129/4885
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof ABL1, TH, CYP3A43 ALDH1A1 1008/4885SMN1; SMN2 4531/4885BRPF1 1796/4885
US-12590066-B2 Fused-heterocyclyl-carbonohydrazonoyl dicyanide compounds and use thereof H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, CLIC1 ALDH1A1 592/4885SMN1; SMN2 2395/4885BRPF1 4446/4885
US-12110286-B2 Benzimidazolone derived inhibitors of BCL6 BCL6, BCL6B, BCL3 ALDH1A1 1654/4885SMN1; SMN2 3864/4885BRPF1 116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.