Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 11/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963482 | 0.84 | TLR7 (0.36) | — | |
| SCHEMBL12933348 | 0.79 | NUDT1 (0.40) | — | |
| SCHEMBL7171839 | 0.76 | APP (0.33) | — | |
| SCHEMBL7172459 | 0.73 | LMNA (0.50) | — | |
| SCHEMBL5400854 | 0.71 | MAPT (0.32) | — | |
| SCHEMBL7172047 | 0.71 | PDE10A (0.36) | GLP1RMAP4K4 | |
| SCHEMBL7172045 | 0.71 | LMNA (0.36) | GLP1R | |
| SCHEMBL21360997 | 0.71 | PGK1 (0.36) | PGK1MAP4K4 | |
| SCHEMBL14909350 | 0.70 | KHK (0.54) | PGK1 | |
| SCHEMBL25083596 | 0.69 | JAK2 (0.36) | PGK1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |