Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 3/20 | 0.44 |
| ▸ | CCND1 | P24385 | 3/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5863451 | 0.89 | ADRB1 (0.55) | ADRB1MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL709125 | 0.88 | MAPT (0.50) | ADRB1MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL5863292 | 0.87 | ALDH1A1 (0.49) | ADRB1MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL15547292 | 0.86 | ADRB1 (0.58) | ADRB1MAPTKDM4EALDH1A1USP2 | |
| SCHEMBL3464205 | 0.84 | MAPT (0.54) | ADRB1MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL19212046 | 0.84 | MAPT (0.46) | ADRB1MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL5864094 | 0.84 | ALDH1A1 (0.52) | ADRB1MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL62795 | 0.83 | HPGD (0.56) | ADRB1MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL21430924 | 0.83 | MAPT (0.55) | ADRB1MAPTKDM4EALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL23044907 | 0.82 | MAPT (0.54) | ADRB1MAPTKDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999020606-A2 | PIPERIDINES AND PIPERAZINES AS PLATELET AGGREGATION INHIBITORS | J. URIACH & CIA. S.A. (ES) | 1999-04-29 | — | — | WO | disclosed |