Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20060315 | 0.85 | NR3C1 (0.45) | MEN1KMT2AKDM4EMAPTALOX15 | |
| SCHEMBL1065002 | 0.84 | MEN1 (0.69) | MEN1KMT2AHDAC1KDM4EMAPT | |
| SCHEMBL9197749 | 0.75 | HDAC6 (0.50) | MEN1KMT2AHDAC1KDM4EMAPT | |
| SCHEMBL2019296 | 0.75 | MEN1 (0.67) | MEN1KMT2AHDAC1KDM4EMAPT | |
| SCHEMBL2065219 | 0.72 | HDAC1 (0.59) | MEN1KMT2AHDAC1KDM4EMAPT | |
| SCHEMBL9201046 | 0.72 | HDAC6 (0.57) | MEN1KMT2AHDAC1PTGER4PTGER2 | |
| SCHEMBL9198791 | 0.71 | HDAC6 (0.46) | MEN1KMT2AHDAC1KDM4EMAPT | |
| SCHEMBL17502340 | 0.70 | HDAC1 (0.76) | MEN1KMT2AHDAC1MAPTHDAC7 | |
| SCHEMBL3707181 | 0.70 | MEN1 (0.62) | MEN1KMT2AHDAC1KDM4EMAPT | |
| SCHEMBL24754397 | 0.69 | MEN1 (0.67) | MEN1KMT2AHDAC1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |