SCHEMBL83529

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL83487	0.99	CUL4A (0.48)	CUL4AHPGDMAPTHIF1AALDH1A1
	SCHEMBL25693763	0.82	HTT (0.50)	CUL4AHPGDMAPTHIF1AALDH1A1
	SCHEMBL83530	0.81	SMN1; SMN2 (0.51)	CUL4AHPGDMAPTALDH1A1HTR2A
	SCHEMBL83168	0.77	METAP2 (0.36)	CUL4AHPGDMAPTHIF1AALDH1A1
	SCHEMBL82700	0.76	METAP2 (0.35)	CUL4AHPGDMAPTHIF1AALDH1A1
	SCHEMBL12395049	0.76	CUL4A (0.39)	CUL4AHTR2AHTR2CHTR2BHTT
	SCHEMBL83400	0.72	CUL4A (0.38)	CUL4AHPGDMAPTHIF1AALDH1A1
	SCHEMBL19719450	0.71	HTT (0.52)	HPGDMAPTALDH1A1HTTLMNA
	SCHEMBL13285331	0.70	ALDH1A1 (0.42)	HPGDMAPTHIF1AALDH1A1NPY5R
	SCHEMBL3951466	0.70	JAK3 (0.71)	HTR2CJAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.