Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718264 | 0.78 | MAPT (0.47) | KMT2AHPGDNPSR1LMNANPY5R | |
| SCHEMBL83858 | 0.75 | ELOVL1 (0.33) | MEN1KMT2AHPGDNPSR1NPC1 | |
| SCHEMBL1318813 | 0.73 | MAPT (0.48) | MEN1KMT2AHPGDNPSR1LMNA | |
| SCHEMBL2640795 | 0.73 | HPGD (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL18951798 | 0.73 | HRH4 (0.43) | LMNAPRCPCYP17A1 | |
| SCHEMBL20575880 | 0.72 | PRCP (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL83529 | 0.72 | CUL4A (0.49) | CUL4APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL83487 | 0.71 | CUL4A (0.48) | CUL4APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1320233 | 0.71 | MAP4K1 (0.38) | HPGDNPSR1LMNANPY5RMAPT | |
| SCHEMBL5190994 | 0.71 | NOS2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129526-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| US-7973028-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-07-05 | — | — | US | disclosed |
| US-7968537-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-28 | — | — | US | disclosed |
| EP-1622879-B1 | PYRIMIDINE COMPOUNDS AND PESTS CONTROLLING COMPOSITIONS CONTAINING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2011-04-27 | — | — | EP | disclosed |
| US-7928110-B2 | Pyrimidine compound and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7732448-B2 | Pyrimidine compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20100036117-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20090209519-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-20 | — | — | US | disclosed |
| US-20090209518-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-20 | — | — | US | disclosed |
| US-20090203674-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20060199800-A1 | Pyrimidine compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-09-07 | — | — | US | disclosed |
| EP-1622879-A1 | PYRIMIDINE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004099160-A1 | PYRIMIDINE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199800-A1 | Pyrimidine compounds and pests controlling composition containing the same | C5, C1S, TYMS | CUL4A 193/4885PSEN1 3728/4885PSEN2 3684/4885 |
| US-20090203674-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, C9 | CUL4A 159/4885PSEN1 3479/4885PSEN2 4103/4885 |
| US-20090209518-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, C9 | CUL4A 172/4885PSEN1 3445/4885PSEN2 4070/4885 |
| US-20100036117-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, CCNB3 | CUL4A 273/4885PSEN1 3728/4885PSEN2 3652/4885 |
| US-20090209519-A1 | PYRIMIDINE COMPOUND AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | C5, C1S, C9 | CUL4A 168/4885PSEN1 3409/4885PSEN2 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.