Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.48 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.48 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.48 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008237 | 0.88 | KDM4E (0.46) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL31094341 | 0.86 | POLM (0.60) | SOAT1KDM4EPOLMPOLKPOLL | |
| SCHEMBL5167656 | 0.86 | POLM (0.60) | SOAT1KDM4EPOLMPOLKPOLL | |
| SCHEMBL15709637 | 0.85 | SOAT1 (0.49) | SOAT1KDM4EPOLMPOLKPOLL | |
| SCHEMBL34470595 | 0.84 | KDM4E (0.60) | SOAT1KDM4EPOLMPOLKPOLL | |
| SCHEMBL27544260 | 0.84 | KDM4E (0.60) | SOAT1KDM4EPOLMPOLKPOLL | |
| SCHEMBL19717844 | 0.82 | MEN1 (0.65) | KDM4EPOLMPOLKPOLLPOLH | |
| SCHEMBL18261165 | 0.81 | KMT2A (0.56) | KDM4EPOLMPOLKPOLLPOLH | |
| SCHEMBL8351886 | 0.81 | PPARG (0.48) | KDM4EPOLMPOLKPOLLPOLH | |
| SCHEMBL8355648 | 0.81 | P2RX7 (0.47) | KDM4EPOLMPOLKPOLLPOLH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999029640-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR | EISAI CO., LTD. (JP) | 1999-06-17 | — | — | WO | disclosed |