SCHEMBL8355648

SCHEMBL8355648

CCCCCCCCCCC(=O)OOc1ccccc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 1/20 0.46
RECQL P46063 1/20 0.46
PPARG P37231 1/20 0.45
POLM Q9NP87 1/20 0.45
POLK Q9UBT6 1/20 0.45
POLL Q9UGP5 1/20 0.45
POLH Q9Y253 1/20 0.45
CES2 O00748 2/20 0.43
CES1 P23141 2/20 0.43
NR1I2 O75469 1/20 0.42
LMNA P02545 1/20 0.42
CHRM2 P08172 1/20 0.42
CYP3A4 P08684 1/20 0.42
ADRA2A P08913 1/20 0.42
MAPT P10636 1/20 0.42
OPRK1 P41145 1/20 0.42
HTR2B P41595 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16149020 0.98 MEN1 (0.47) P2RX7MEN1KMT2AKDM4ERECQL
SCHEMBL27345094 0.87 AOC2 (0.43) MEN1KMT2AKDM4ERECQLLMNA
SCHEMBL18261165 0.85 KMT2A (0.56) MEN1KMT2AKDM4ERECQLPPARG
SCHEMBL8351886 0.85 PPARG (0.48) MEN1KMT2AKDM4ERECQLPPARG
SCHEMBL11591925 0.84 KDM4E (0.59) P2RX7MEN1KMT2AKDM4ERECQL
SCHEMBL9181885 0.84 KDM4E (0.59) P2RX7MEN1KMT2AKDM4ERECQL
SCHEMBL18261164 0.83 KMT2A (0.57) MEN1KMT2AKDM4ERECQLPPARG
SCHEMBL8934268 0.83 KDM4E (0.60) P2RX7MEN1KMT2AKDM4ERECQL
SCHEMBL19717844 0.82 MEN1 (0.65) MEN1KMT2AKDM4ERECQLPPARG
SCHEMBL8353141 0.81 CNR1 (0.47) KMT2AKDM4EPPARGPOLMPOLK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999029640-A2 COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR EISAI CO., LTD. (JP) 1999-06-17 WO disclosed