Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974684 | 0.93 | KDM4E (0.56) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL974686 | 0.88 | KDM4E (0.52) | MEN1KMT2AKDM4ERECQLMAPT | |
| SCHEMBL15655618 | 0.86 | ALDH1A1 (0.56) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL16800398 | 0.85 | KDM4E (0.88) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL725982 | 0.85 | KDM4E (0.88) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL29135334 | 0.85 | KDM4E (0.88) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL6328818 | 0.85 | KDM4E (0.88) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL1858148 | 0.85 | KDM4E (0.88) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL727072 | 0.85 | KDM4E (0.88) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL44212 | 0.85 | KDM4E (0.88) | MEN1KMT2AKDM4ERECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107427612-A | Medical devices degradable on demand | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 2017-12-01 | — | — | CN | claimed |
| EP-3471673-A1 | REUSABLE INSTRUMENT HANDLE WITH SINGLE- USE TIP | Katalyst Surgical, LLC (US) | 2019-04-24 | — | — | EP | disclosed |
| WO-2017218161-A1 | REUSABLE INSTRUMENT HANDLE WITH SINGLE- USE TIP | KATALYST SURGICAL, LLC (US) | 2017-12-21 | — | — | WO | disclosed |
| CN-107427612-A | Medical devices degradable on demand | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 2017-12-01 | — | — | CN | disclosed |