Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 6/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.49 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.49 |
| ▸ | TK2 | O00142 | 9/20 | 0.35 |
| ▸ | TK1 | P04183 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353085 | 0.85 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5TK2 | |
| SCHEMBL8193378 | 0.85 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5TK2 | |
| SCHEMBL8352756 | 0.85 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5TK2 | |
| SCHEMBL8357808 | 0.85 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5TK2 | |
| SCHEMBL8357825 | 0.83 | PLA2G2A (0.59) | PLA2G2APLA2G10PLA2G1BPLA2G5TK2 | |
| SCHEMBL8357815 | 0.81 | PLA2G2A (0.45) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL16854613 | 0.80 | PLA2G2A (0.50) | PLA2G2APLA2G10PLA2G1BPLA2G5TK2 | |
| SCHEMBL9137670 | 0.79 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL497520 | 0.79 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8917115 | 0.79 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745068-A4 | HETEROARYL-SUBSTITUTED DEOXY GLYCERO-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS INC (US) | 1997-02-26 | — | — | EP | disclosed |
| EP-0745068-A1 | HETEROARYL-SUBSTITUTED DEOXY GLYCERO-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 1996-12-04 | — | — | EP | disclosed |
| WO-1996016041-A1 | HETEROARYL-SUBSTITUTED DEOXY GLYCERO-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS INC. (US) | 1996-05-30 | — | — | WO | disclosed |