Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13099807 | 0.95 | ALDH1A1 (0.38) | ALDH1A1THRB | |
| SCHEMBL7774222 | 0.95 | ALDH1A1 (0.38) | ALDH1A1THRB | |
| Ether SCHEMBL8844417 | 0.92 | ALDH1A1 (0.36) | ALDH1A1THRB | |
| SCHEMBL8987964 | 0.89 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL9512363 | 0.89 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL9683851 | 0.89 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL45482 | 0.89 | THRB (0.36) | ALDH1A1THRB | |
| SCHEMBL13616508 | 0.86 | THRB (0.35) | ALDH1A1THRB | |
| SCHEMBL17460095 | 0.86 | THRB (0.35) | ALDH1A1THRB | |
| SCHEMBL21291961 | 0.86 | THRB (0.35) | ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018309-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2024-01-18 | — | — | US | disclosed |
| US-11802182-B2 | Silicone hydrogel contact lenses | ALCON INC. (CH) | 2023-10-31 | — | — | US | disclosed |
| US-20170166673-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2017-06-15 | — | — | US | disclosed |
| US-20170107255-A1 | APELIN POLYPEPTIDES | AMGEN INC. (US) | 2017-04-20 | — | — | US | disclosed |
| US-5861107-A | ESTER INTERCHANGE OF 1,3-PROPANEDIOL COMPOUNDS WITH CARBONIC ACID ESTERS; DISTILLATIVE DEPOLYMERIZATION; CATALYSIS WITH TITANIUM OR ZIRCONIUM COMPOUND; PHOSPHORUS OR SULFUR COMPOUND STABILIZER | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | disclosed |
| EP-0816354-A1 | Process for preparing and stabilisation of aliphatic six-membered cyclic carbonates | BAYER AG (DE) | 1998-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170107255-A1 | APELIN POLYPEPTIDES | APLNR, FABP3, AP3B1 | ALDH1A1 3602/4885THRB 3050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.