Naphthalene

Naphthalene

SCHEMBL8353552

O=C(O)CC(=O)O.c1ccc2ccccc2c1

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.53
SRR Q9GZT4 1/20 0.53
PTPN7 P35236 1/20 0.48
KMT2A Q03164 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
MEN1 O00255 2/20 0.48
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
CYP3A4 P08684 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
CES1 P23141 1/20 0.48
MAPK1 P28482 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
AKR1B1 P15121 1/20 0.48
CYP2A6 P11509 1/20 0.47
ALOX12 P18054 1/20 0.47
CYP1A2 P05177 2/20 0.47
PAM P19021 1/20 0.44
KEAP1 Q14145 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL16044499 0.82 NR4A2 (0.61) PTPN7MAPTMAPK1SMN1; SMN2AKR1B1
Biphenyl SCHEMBL1029706 0.82 LMNA (0.58) LDHASRRKMT2ATDP1MEN1
Biphenyl SCHEMBL6525433 0.82 LMNA (0.58) LDHASRRKMT2ATDP1MEN1
Naphthalene SCHEMBL28240036 0.82 PTPN7 (0.48) PTPN7KMT2ATDP1MEN1MAPT
Naphthalene SCHEMBL30124954 0.82 NR4A2 (0.61) PTPN7MAPTMAPK1SMN1; SMN2AKR1B1
Naphthalene SCHEMBL7201843 0.81 CYP2A6 (0.61) PTPN7KMT2ATDP1MEN1MAPT
Naphthalene SCHEMBL10590639 0.81 CYP2A6 (0.61) PTPN7KMT2ATDP1MEN1MAPT
Naphthalene SCHEMBL1478520 0.81 CYP2A6 (0.61) PTPN7KMT2ATDP1MEN1MAPT
Naphthalene SCHEMBL3278833 0.81 CYP2A6 (0.61) PTPN7KMT2ATDP1MEN1MAPT
Naphthalene SCHEMBL373901 0.81 CYP2A6 (0.61) PTPN7KMT2ATDP1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462363-A Preparation method of naphthalene acetic acid 杭州乐敦科技有限公司 2025-02-18 CN disclosed
US-5879438-A CONTAINING SPECIFIC ELECTRON ACCEPTING LIGHTFASTNESS PROVIDING AGENT THE PILOT INK CO., LTD. (JP) 1999-03-09 US disclosed
EP-0644182-B1 Cyclohexane derivatives useful as potassium channel openers EISAI CO LTD (JP) 1998-05-13 EP disclosed
US-5605907-A USEFUL AS A PREVENTIVE AND THERAPEUTIC AGENT FOR DISEASES AGAINST WHICH A POTASSIUM CHANNEL OPENING ACTION IS EFFICACIOUS EISAI CO., LTD. (JP) 1997-02-25 US disclosed
US-5478839-A Potassium channel modulator, bronchodilator agent, muscle relaxants, vasodilator EISAI CO., LTD. (JP) 1995-12-26 US disclosed
EP-0644182-A1 Cyclohexane derivatives useful as potassium channel openers Eisai Co., Ltd. (JP) 1995-03-22 EP disclosed