⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265873 | 0.92 | — | — | |
| SCHEMBL26477012 | 0.74 | ALDH1A1 (0.30) | — | |
| SCHEMBL30140506 | 0.73 | ALDH1A1 (0.36) | — | |
| SCHEMBL594044 | 0.73 | TSHR (0.35) | — | |
| SCHEMBL14273633 | 0.72 | — | — | |
| SCHEMBL3913124 | 0.72 | — | — | |
| SCHEMBL11221623 | 0.71 | — | — | |
| SCHEMBL436734 | 0.71 | — | — | |
| SCHEMBL18138950 | 0.71 | — | — | |
| SCHEMBL11244658 | 0.71 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774764-A1 | BENZOTHIOPHENES AND RELATED COMPOUNDS AS STING AGONISTS | Merck Sharp&Dohme Corp. (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3753935-A1 | SUBSTITUTED DIALKYL(OXIDO)-LAMBDA4-SULFANYLIDENE NICOTINAMIDE DERIVATIVES AS KINASE INHIBITORS | ALLERGAN, INC. (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-3753935-A1 | SUBSTITUTED DIALKYL(OXIDO)-LAMBDA4-SULFANYLIDENE NICOTINAMIDE DERIVATIVES AS KINASE INHIBITORS | ALLERGAN, INC. (US) | 2020-12-23 | — | — | EP | disclosed |
| CN-111971277-A | Benzothiophenes and related compounds as STING agonists | 默沙东公司 | 2020-11-20 | — | — | CN | disclosed |
| US-10793557-B2 | Sting agonist compounds | MERCK SHARP & DOHME CORP. (US) | 2020-10-06 | — | — | US | disclosed |
| EP-3080105-B1 | SUBSTITUTED DIALKYL(OXIDO)-LAMBDA4-SULFANYLIDENE NICOTINAMIDE DERIVATIVES AS KINASE INHIBITORS | ALLERGAN INC (US) | 2020-09-02 | — | — | EP | disclosed |
| EP-3378882-B1 | METHOD FOR PRODUCING POLYETHYLENE GLYCOL HAVING TERMINAL CARBOXY GROUP | NOF CORP (JP) | 2020-06-17 | — | — | EP | disclosed |
| WO-2019195124-A1 | BENZOTHIOPHENES AND RELATED COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-10-10 | — | — | WO | disclosed |
| US-20190300513-A1 | STING AGONIST COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2019-10-03 | — | — | US | disclosed |
| US-10407543-B2 | Method for producing polyethylene glycol having terminal carboxyl group | NOF CORPORATION (JP) | 2019-09-10 | — | — | US | disclosed |
| US-5674697-A | High sensitivity immunoassay for polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans | ECOCHEM RESEARCH, INC. (US) | 1997-10-07 | — | — | US | disclosed |
| US-5633279-A | 5-substituted derivatives of mycophenolic acid | SYNTEX (U.S.A.) INC. (US) | 1997-05-27 | — | — | US | disclosed |
| EP-0745073-A1 | 5-SUBSTITUTED DERIVATIVES OF MYCOPHENOLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1996-12-04 | — | — | EP | disclosed |
| US-5538852-A | QUALITATIVE OR QUANTITATIVE ANALYSIS WITH COMPETITORS AND ANTIBODIES | ECOCHEM RESEARCH, INC. (US) | 1996-07-23 | — | — | US | disclosed |
| WO-1996018616-A1 | SUBSTITUTED 2-AMINOPYRIDINES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | disclosed |
| US-5493030-A | CHEMICAL INTERMEDIATES | SYNTEX (U.S.A.) INC. (US) | 1996-02-20 | — | — | US | disclosed |
| WO-1995022538-A1 | 5-SUBSTITUTED DERIVATIVES OF MYCOPHENOLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1995-08-24 | — | — | WO | disclosed |
| WO-1993012137-A1 | PHARMACEUTICAL COMPOSITIONS | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1993-06-24 | — | — | WO | disclosed |
| US-4958037-A | HYPOTENSIVE, VASODILATION | AMERICAN CYANAMID COMPANY (US) | 1990-09-18 | — | — | US | disclosed |
| EP-0213313-A2 | Precursors and synthesis of methyl-9-oxo-11 alpha, 16-dihydroxy-16-vinyl-5-cis-13-trans prostadienoates | AMERICAN CYANAMID COMPANY (US) | 1987-03-11 | — | — | EP | disclosed |