Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13900119 | 0.83 | CCR2 (0.48) | CCR2ALDH1A1LMNAHPGDHTT | |
| SCHEMBL8357797 | 0.74 | F10 (0.54) | CCR2ALDH1A1LMNAHPGDHTT | |
| SCHEMBL13900112 | 0.72 | F10 (0.46) | ALDH1A1LMNAHPGDHTTNPSR1 | |
| SCHEMBL8358870 | 0.71 | F10 (0.51) | CCR2LMNAF10NPC1RAB9A | |
| SCHEMBL1675306 | 0.67 | F10 (0.68) | F10 | |
| SCHEMBL8358657 | 0.67 | PTGS2 (0.71) | CCR2ALDH1A1F10 | |
| SCHEMBL3961949 | 0.66 | CCR2 (1.00) | CCR2 | |
| SCHEMBL1675000 | 0.65 | F10 (0.70) | CCR2F10 | |
| SCHEMBL8358922 | 0.65 | F10 (0.41) | ALDH1A1LMNAHPGDHTTNPSR1 | |
| SCHEMBL13900118 | 0.65 | F10 (0.67) | CCR2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003044014-A1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-05-30 | — | — | WO | disclosed |