Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13900112 | 0.85 | F10 (0.46) | F10LMNAALDH1A1HPGDHTT | |
| SCHEMBL8354980 | 0.80 | RAB9A (0.48) | F10LMNAALDH1A1HPGDL3MBTL1 | |
| SCHEMBL13900119 | 0.79 | CCR2 (0.48) | F10LMNAALDH1A1HPGDHTT | |
| SCHEMBL8357797 | 0.77 | F10 (0.54) | F10LMNAALDH1A1HPGDHTT | |
| SCHEMBL1675306 | 0.73 | F10 (0.68) | F10F2 | |
| SCHEMBL8358870 | 0.72 | F10 (0.51) | F10LMNAL3MBTL1CYP2C19CYP3A4 | |
| SCHEMBL1095599 | 0.66 | F10 (0.47) | F10HPGDNPC1RAB9A | |
| SCHEMBL7505956 | 0.65 | RAB9A (0.51) | F10HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7505962 | 0.65 | RAB9A (0.51) | F10HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8355123 | 0.65 | CCR2 (0.46) | F10LMNAALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003044014-A1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-05-30 | — | — | WO | disclosed |