Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7133272 | 0.81 | ALDH1A1 (0.32) | ALDH1A1NFE2L2TRPA1 | |
| SCHEMBL7132515 | 0.78 | — | — | |
| SCHEMBL7136225 | 0.78 | — | — | |
| SCHEMBL7132212 | 0.78 | KDM4E (0.40) | NFE2L2KDM4E | |
| SCHEMBL7134964 | 0.77 | TRIM58 (0.35) | ALDH1A1KMT2AMEN1HPGDLMNA | |
| SCHEMBL9639871 | 0.76 | ALDH1A1 (0.34) | ALDH1A1KMT2AMEN1CYP3A4HPGD | |
| SCHEMBL14909 | 0.76 | NFE2L2 (0.55) | ALDH1A1KMT2AMEN1CYP3A4NFE2L2 | |
| SCHEMBL29377009 | 0.76 | NFE2L2 (0.55) | ALDH1A1KMT2AMEN1CYP3A4NFE2L2 | |
| SCHEMBL297297 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1CYP3A4NFE2L2 | |
| Hydrogen Sulfide SCHEMBL27500079 | 0.74 | NFE2L2 (0.53) | ALDH1A1KMT2AMEN1CYP3A4NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986124-A | Method for making compounds containing hydrocarbonoxysilyi groups by hydrosilylation using hydrido (hydrocarbonoxy) silane compounds | DOW CORNING ASIA, LTD. (JP) | 1999-11-16 | — | — | US | disclosed |