Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510544 | 0.87 | GAA (0.48) | GAALMNANPC1RAB9APTGDR2 | |
| SCHEMBL10732824 | 0.81 | GAA (0.50) | GAALMNAPTGDR2SLC40A1EDNRA | |
| SCHEMBL8357447 | 0.79 | SLC40A1 (0.49) | GAALMNANPC1RAB9APTGDR2 | |
| SCHEMBL8358974 | 0.76 | GAA (0.50) | GAALMNAPTGDR2SLC40A1EDNRA | |
| SCHEMBL8358748 | 0.76 | GAA (0.53) | GAALMNAPTGDR2EDNRAMEN1 | |
| SCHEMBL8358999 | 0.75 | TSHR (0.45) | GAANPC1RAB9ASLC40A1PKM | |
| SCHEMBL8358849 | 0.73 | GAA (0.46) | GAALMNASLC40A1EDNRAMEN1 | |
| SCHEMBL9831332 | 0.72 | ALDH1A1 (0.44) | GAANPC1RAB9ASLC40A1KMT2A | |
| SCHEMBL8356883 | 0.71 | SMN1; SMN2 (0.50) | GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL8376128 | 0.71 | ALDH1A1 (0.53) | GAALMNAPKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992010098-A1 | SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS | MONSANTO COMPANY (US) | 1992-06-25 | — | — | WO | claimed |
| US-5880066-A | COMPOSITION COMPRISING TRIAZOLOPYRIMIDINE SULFONAMIDE HERBICIDE AND OXAZOLIDINE DICHLOROACETAMIDE ANTIDOTE | MONSANTO COMPANY (US) | 1999-03-09 | — | — | US | disclosed |
| EP-0565593-B1 | REDUCING PESTICIDAL INTERACTIONS IN CROPS | MONSANTO CO (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5484760-A | AMIDES | MONSANTO COMPANY (US) | 1996-01-16 | — | — | US | disclosed |
| US-4822404-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1989-04-18 | — | — | US | disclosed |
| US-4772720-A | Process for the preparation of intermediates useful for making herbicidal sulfonamides derived from substituted 2-amino-1,2,4-triazolo(1,5-A)pyrimidines | THE DOW CHEMICAL COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| US-4650892-A | ARYLSULFONAMIDE AND DIMETHYL N-CYANODTHIOIMINO CARBONATE | THE DOW CHEMICAL COMPANY (US) | 1987-03-17 | — | — | US | disclosed |
| US-4638075-A | CHEMICAL INTERMEDIATES FOR TRIAZOLO (1,5A) PYRIMIDINES | THE DOW CHEMICAL COMPANY (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0188225-A1 | Process for the preparation of herbicidal sulfonamides derived from substituted 2-amino-1,2,4 triazolo (1,5-a) pyrimidines and novel intermediates provided therein | THE DOW CHEMICAL COMPANY (US) | 1986-07-23 | — | — | EP | disclosed |
| EP-0150974-A2 | Novel sulfonamides derived from substituted 2-amino-1,2,4-triazolo(1,5-a)pyrimidines and compositions and methods of controlling undesired vegetation | THE DOW CHEMICAL COMPANY (US) | 1985-08-07 | — | — | EP | disclosed |