Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354585 | 0.98 | LMNA (0.61) | LMNADRD4USP2HPGDNPC1 | |
| SCHEMBL3148838 | 0.86 | DRD4 (0.48) | LMNADRD4MEN1KMT2AHRH3 | |
| SCHEMBL8256016 | 0.86 | LMNA (0.52) | LMNADRD4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3577293 | 0.86 | DRD4 (0.64) | LMNADRD4NPC1KMT2AHRH3 | |
| SCHEMBL3158672 | 0.84 | DRD4 (0.49) | LMNADRD4HRH3SIGMAR1ALDH1A1 | |
| SCHEMBL14174854 | 0.83 | KMT2A (0.52) | LMNAMEN1KMT2AHRH3GAA | |
| SCHEMBL3143293 | 0.81 | LMNA (0.54) | LMNAMEN1KMT2AHRH3SIGMAR1 | |
| SCHEMBL30921473 | 0.81 | DRD4 (0.49) | LMNADRD4HRH3SIGMAR1ALDH1A1 | |
| SCHEMBL8355269 | 0.80 | LMNA (0.42) | LMNADRD4HPGDNPC1RAB9A | |
| SCHEMBL3157089 | 0.80 | LMNA (0.56) | LMNADRD4MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048081-A2 | GLYCINAMIDES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-06-12 | — | — | WO | disclosed |